HPLC Column, RP C4 Butyl, 5um, 4.0mm ID x 250mm Length, 100A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent RP C4™ is a reversed-phase HPLC stationary phase designed for the separation of hydrophobic and neutral compounds where less retention is desired than with traditional C8 or C18 phases. Manufactured using a four-carbon butyl ligand bonded to ultra-high purity silica and fully double end capped, this stationary phase provides reproducible chromatographic performance and is widely used as an alternative in USP methods requiring L26 chemistry. Its reduced hydrophobicity compared to longer-chain bonded phases makes it particularly useful for rapid analyses, routine testing, and method development.
68504-25P-4 is an HPLC column packed with 5 µm RP C4™ particles featuring a 100 Å pore size in a 4.0 mm ID x 250 mm format. The 250 mm length provides maximum chromatographic resolution and peak capacity within the RP C4™ product family, while the 5 µm particles allow operation at higher flow rates with lower backpressure than smaller particle columns. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, temperature, and system configuration.
This column is commonly used for hydrophobic and neutral compounds in reversed-phase HPLC when reduced retention is desirable. Compared to C8 phases, RP C4™ typically provides lower retention, making it useful for compounds that may otherwise be excessively retained on more hydrophobic stationary phases. The 250 mm format is particularly valuable for difficult separations requiring maximum resolving power and peak capacity.
Key Benefits
RP C4™ stationary phase
USP L26 equivalent chemistry
Butyl bonded phase
Fully double end capped
Ultra-high purity silica support
Less retention than C8 phases
Suitable for rapid analyses
Lower backpressure than smaller particle columns
5 µm particle size
Maximum chromatographic resolution
Typical Applications
USP L26 methods
Method development
Method scouting
Hydrophobic compound analysis
Neutral compound analysis
Reversed-phase HPLC
Pharmaceutical analysis
Quality control testing
Research and development
Complex separations requiring high resolution
Specifications
Product Type: HPLC Column
Stationary Phase: RP C4™
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 4.0 mm ID x 250 mm
Length: 250 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for hydrophobic and neutral compounds
Provides less retention than C8 stationary phases
Suitable for rapid reversed-phase separations
The 250 mm length provides maximum resolution and peak capacity for challenging separations
5 µm particles allow higher flow rates with lower backpressure
Fully double end capped to minimize secondary interactions
Frequently used for method development and scouting studies
Excellent alternative for USP L26 methods
This is a Special Order Item